Metabolic robustness, the ability of a metabolic system to buffer changes in its environment, is not always a welcome feature for microbiologists: it interferes with metabolic engineering or prevents that antibiotics kill bacteria. Therefore it is important to understand the mechanisms that enable metabolic robustness. A massively parallel CRISPRi screen demonstrated that E. colimetabolism is very robust against knockdowns of enzymes, and multi-omics data revealed the mechanisms behind it. In the future, the researchers want to apply this knowledge to build better models of metabolism, which enable rational-design of industrial microbes.
* This article was originally published here
Subscribe to:
Post Comments (Atom)
I burned 300 calories hanging Christmas lights (and you can too) - Journée Mondiale
I burned 300 calories hanging Christmas lights (and you can too) Journée Mondiale * This article was originally published here ...
-
Increasing nut consumption by just half a serving (14 g or ½ oz) a day is linked to less weight gain and a lower risk of obesity, suggests a...
-
Contrary to accepted knowledge, blood can bring more oxygen to mice brains when they exercise because the increased respiration packs more o...
-
While some diets load up on protein and other diets dictate protein sources, it can be hard to know what to consume while managing weight or...
No comments:
Post a Comment